
包纯洁(邮箱chunjie@njucm.edu.cn),副教授,硕士生研究生导师。北京大学药剂学博士,南京中医药大学校C类特聘引进人才,中华中医药学会会员。
主要从事恶性肿瘤治疗与中医药研究,研究兴趣:(1)前沿交叉技术驱动的中药活性成分抗肿瘤活性及作用机制研究;(2)中医药理论指导下的中药活性成分肿瘤靶向递送系统开发研究。现主持江苏省自然科学青年基金、江苏省高等学校自然科学研究面上项目(A类资助)等,参与国家自然科基金面上项目2项。至今已在Nano-Micro Letters、Bioactive Materials、Advanced Drug Delivery Reviews等高水平期刊发表15篇学术论文,其中以第一作者/通讯作者身份发表SCI论文7篇。目前担任Science of Traditional Chinese Medicine等学术杂志青年编委,担任Advanced Drug Delivery Reviews等国际学术期刊的审稿人。
代表性研究论文
[1] Bao C#, Duan J#, Xie Y#, Feng X, Cui W, Chen S, Li P, Liu Y, Wang J, Wang G, Lu W*. Bioorthogonal Engineered Virus-Like Nanoparticles for Efficient Gene Therapy. Nanomicro Lett. 2023 Aug 12;15(1):197.
[2] Bao C#, Duan J#, Xie Y#, Liu Y, Li P, Li J, Zhao H, Guo H, Men Y, Ren Y, Xu J, Wang G, Lu W*. A novel oncogenic enhancer of estrogen receptor-positive breast cancer. Mol Ther Nucleic Acids. 2022 Aug 24;29:836-851.
[3] Liu M#, Bao C#, Liang X, Ji X, Zhao L, Yao A, Guo S, Duan J*, Zhao M*, Duan J*. Specific molecular weight of Lycium barbarum polysaccharide for robust breast cancer regression by repolarizing tumor-associated macrophages. Int J Biol Macromol. 2024, 261(Pt 1): 129674.
[4] Duan J#, Liu M#, Liu Y#, Liang X, Cao C, Yao A, Zhao L, Guo S, Qian D, Bao C*, Zhao M*, Duan J*. Comparative study on physicochemical characterization and immunomodulatory activities of neutral and acidic Lycium barbarum polysaccharides. Biomed Pharmacother. 2024, 181: 117659.
[5] Duan J#, Bao C#, Xie Y#, Guo H, Liu Y, Li J, Liu R, Li P, Bai J, Yan Y, Mu L, Li X, Wang G, Lu W*. Targeted core-shell nanoparticles for precise CTCF gene insert in treatment of metastatic breast cancer. Bioact Mater. 2022, 11: 1-14.