于小轩（邮箱：xxyu@njucm.edu.cn）, 药理学博士，副教授，硕士研究生导师, 南京中医药大学校C类特聘教授，入选江苏省中医药学会青年科技人才托举工程，中国药理学会生化与分子药理委员会专业委员，江苏省中西医结合学会血液病专业委员会青年委员。

主要从事白血病免疫治疗的探索及其药物干预研究。迄今在Acta Pharmaceutica Sinica B，Journal of Medicinal Chemistry等期刊上发表SCI论文20余篇。主持国家自然科学基金面上项目，国家自然科学基金青年基金项目C类等国家级与省部级自然科学基金课题9项，主参编《食品生物技术实验》教材，指导本科生获得“恩三杯”南京中医药大学第十八届大学生课外学术科技作品竞赛三等奖。目前担任Journal for ImmunoTherapy of Cancer, Journal of Medicinal Chemistry，Signal Transduction and Targeted Therapy等杂志审稿专家。

代表性研究论文：

(1) Huijing Wang#; Fengyu Jiang #; An Pan #; Chenlong Jin; Yangyang Xue; Wenjie Liu; Renjun Gu; Yanyu Zhou; Qiuhong Shen; Tonghui Ma*; Xiaoxuan Yu*.  Inhibition of PGK1 enhances sensitivity to Tyrosine Kinase Inhibitor in T315I-Mutant Leukemia, Acta Pharmaceutica Sinica B, 2025.

(2) Xiaoxuan Yu#*; Yanyu Zhou#; Shibo Sun; Wan Zhang; Jianqiang Xu*; Wukun Liu*. Isoalantolactone induces AML pyroptosis and potentiates anti-PD1 efficacy by targeting selenoprotein TXNRD1, Acta Pharmaceutica Sinica B, 2025.

(3) Teng Yang; Ze Dong; Rong Du; Yiqing Wang; Lu Liu; Yangyang Xue; Xic Zhang; Yonggang Liao; Jianhua Gan; Xiaoxuan Yu*; Yue Hang*; Caiguang Yang* Development of orally bioavailable FTO inhibitors with potent antileukemia efficacy.Journal of Medicinal Chemistry, 2025 Jul 10;68(13):13714-13727.

(4) Xiaomei Li#; Minmin Liu#; Huijing Wang; Jialuo Mao; Xiangying Zhai; Tingting He; Jingkun Ma; Yubo Zhou; Wei Lu; Xiaoxuan Yu*; Jia Li* and Shulei Zhu*. Design, synthesis, and biological evaluation of WEE1 degraders via HSP90-mediated targeting chimeras for target therapy of Acute Myeloid Leukemia. European Journal of Medicinal Chemistry, 2025 Mar 14; 290:117512.

(5) Xiaoxuan Yu#; Yanyu Zhou#; Xiaoyan Ma; Wan Zhang; Fuwei Li; Fengyu Jiang; Yawen Wang; Qin Zhang; Wukun Liu*. Erlotinib-gold(I) complex induces leukemia cell DC differentiation and remodels the immunosuppressive microenvironment, Journal of Medicinal Chemistry, 2024 Dec 26; 67(24): 21795-21810.