张薇（邮箱：zhangwei@njucm.edu.cn），博士，副教授，硕士生研究生导师，现任南京中医药大学免疫学系副主任。江苏省“333人才工程”培养对象，江苏省免疫学会中医药免疫专业委员会常委。

主要从事：1）炎症、感染发生的分子免疫学机制研究；2）天然产物抗炎、抗感染的分子机制研究研究。在免疫分子信号转导、自噬及溶酶体功能调控、线粒体代谢、肺泡再生等方面具有丰富的经验。先后主持国家级与省部级自然科学基金课题3项，参与国家自然科学基金重大项目、国家重点研发计划子课题各1项。在Cell Mol Immunol、Advanced Science、Nature Chemistry、PLoS Pathogens等高水平学术杂志发表研究论文20余篇，授权专利1项，参编中国中医药出版社《医学免疫学》、人民卫生出版社《医学免疫和病原生物实验学》。目前担任Autophagy、Phytomedicine学术杂志审稿专家。

代表性论文

[1] Wei Zhang, Zhou Sha, Yunzhe Tang, Cuiyuan Jin, Wenhua Gao, Changmai Chen,
Lang Yu, Nianyin Lv, Shijia Liu, Feng Xu*, Dandan Wang*, Liyun Shi*. Defective Lamtor5 Leads to Autoimmunity by Deregulating v-ATPase and Lysosomal Acidification. Advanced Science. 2024, 11(22): e2400446.

[2] Wei Zhang, Ningtong Zhuang, Xiaoyi Liu, Long He, Yan He, Paween Mahinthichaichan, Hang Zhang, Yanhua Kang, Yin Lu, Qinan Wu, Dakang Xu, Liyun Shi*. The metabolic regulator Lamtor5 suppresses inflammatory signaling via regulating mTOR-mediated TLR4 degradation. Cell Mol Immunol. 2020, 17(10): 1063-1076.

[3] Feng Wu, Ji-Jie Wang, Yuanjiu Xiao, Quanxin Peng, Yu-Jie Li, Keren Peng, Qianlan Han, Mengran Wei, Yu Qian*, Wei Zhang*, Guoqiang Wang*, Jian-Jun Feng*. Collective synthesis of 1,2,4-trisubstituted, meta- and ortho-substituted arene bioisosteres from bicyclobutanes. Nature Chemistry. 2026, DOI: 10.1038/s41557-026-02097-7.

[4] Wei Zhang, Xiang Chen, Haoyu Zhang, Xiaoling Liu, Changjiang Chen, Nianyin Lv, Yanan Gao, Liuzhou Gao, Liyun Shi*. Oridonin mitigates bacterial pneumonia by regulating mitochondrial integrity and ferroptosis via targeting KEAP1/NRF2 signaling. Biochem Pharmacol. 2025, 242(Pt 2): 117310.

[5] Wei Zhang, Cheng Cheng, Zhou Sha, Changmai Chen, Chengtao Yu, Nianyin Lv, Peng Ji, Xiaohui Wu, Tonghui Ma, Haibo Cheng, Liyun Shi*. Rosmarinic acid prevents refractory bacterial pneumonia through regulating Keap1/Nrf2-mediated autophagic pathway and mitochondrial oxidative stress. Free Radic Biol Med. 2021, 168: 247-257.