沈旭，博士、教授、博士生导师，国家杰出青年科学基金获得者,“新世纪百千万人才工程”国家级人选，享受国务院政府特殊津贴。江苏省中西医结合学会理事、江苏省药理学学会常务理事、江苏省高校生物学学科联盟理事。

沈旭博士近年来的研究工作主要涉及神经退行性疾病 (包括糖尿病及其并发症、阿尔茨海默症和ALS等) 药靶与药物研究。作为项目负责人主持了多项国家级科研项目，如国家高技术研究发展计划 (863计划) 项目、国家杰出青年科学基金项目、国家重大科技专项“十一五”、“十二五”和“十三五”项目以及国家自然科学基金重点项目等。在国际重要学术期刊(如PNAS, Diabetes, Aging Cell等)上发表学术论文300余篇，获授权专利30余项；获国家自然科学二等奖、上海市科技进步一等奖、上海市领军人才以及中国科学院优秀研究生导师等多项科研奖励和荣誉称号。

近5年发表的5篇代表性论文

(i)Jian Lu, Chuzhao Zhang, Jianlu Lv, Xialin Zhu, Xingwu Jiang, Weiqiang Lu, Yin Lu, Zongxiang Tang, Jiaying Wang, Xu Shen. Antiallergic drug desloratadine as a selective antagonist of 5HT 2A receptor ameliorates pathology of Alzheimer's disease model mice by improving microglial dysfunction. Aging Cell, 2021, 20, e13286. 

(ii)Xiaokang Li, Jian Lu, Yixiang Xu, Jiaying Wang, Xiaoxia Qiu, Lei Fan, Baoli Li, Wenwen Liu, Fei Mao, Jin Zhu, Xu Shen, Jian Li. Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease. Acta Pharm Sin B. 2020, 10, 646-666. 

(iii)Jianlu Lv, Wei Wang, Xialin Zhu, Xiaoju Xu, Qiuying Yan, Jian Lu, Xiaofan Shi, Zhengyu Wang, Jinpei Zhou, Xi Huang, Jiaying Wang, Wenhu Duan, Xu Shen. DW14006 as a direct AMPKα1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation. Brain Behav Immun. 2020, 90, 55-69. 

(iv)Xu Xu, Wei Wang, Zhengyu Wang, Jianlu Lv, Xiaoju Xu, Jiawen Xu, Juanzhen Yang, Xialin Zhu, Yin Lu, Wenhu Duan, Xi Huang, Jiaying Wang, Jinpei Zhou, Xu Shen. DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice. Diabetes. 2020, 69, 1974-1988. 

(v)Xialin Zhu, Yun Chen, Xu Xu, Xiaoju Xu, Yin Lu, Xi Huang, Jinpei Zhou, Lihong Hu, Jiaying Wang, Xu Shen. SP6616 as a Kv2.1 inhibitor efficiently ameliorates peripheral neuropathy in diabetic mice. EBioMedicine. 2020, 61, 103061.(封面文章)