人才培养

史丽云

邮箱:shi_liyun@msn.com

职称:教授  博士生导师

个人简介

南京中医药大学教授,博士生导师,医学博士, 科学技术和产业处处长,病原与免疫学系主任。本科毕业于复旦大学,于浙江大学获得医学硕士和博士学位,哈佛大学博士后。入选教育部新世纪优秀人才支持计划,浙江省高校中青年学科带头人,浙江省"151"新世纪人才等;获得全国百篇优秀博士论文、省青年科技奖、省高校科研成果奖等;主要研究方向为肿瘤和炎症发生的免疫学机制及其中医药干预。近年来,在Blood、Oncogene、J Immunol等国际权威学术期刊发表SCI论文40余篇,主持国家自然科学基金、国家重点研发计划课题等15项,主编或副主编教材(专著)3部。现任中国免疫学会中医药免疫分会副主委、中华中医药学会产业分会常务理事、江苏省中西医结合学会理事、浙江省免疫学会常务理事、浙江省医学会微免分会常务委员等。

研究领域
1. 炎症和肿瘤发生的免疫学机制
2. 炎症和肿瘤发生的中医药免疫调控作用及其机制

代表性论文 (* 通讯作者)
1. Shi L*, Wang Y, Z Lu, H Zhang, N Zhuang, B Wang, Z Song, G Chen, C Huang, D Xu, Y Zhang, W Zhang, Y Gao. miR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop. Oncogene.  2017 Mar 23;36(12):1631-1643
2. Kang Y, Zhang H, Zhao Y, Wang Y, Wang W, He Y, Zhang W, Zhang W, Zhang L, Ju Z, Shi L*. Telomere dysfunction disturbs macrophage mitochondrial metabolism and NLRP3 inflammasome through PGC-1α/TNFAIP3 axis. Cell Rep. In press
3. Ying H, Kang Y, Zhang H, Zhao D, Xia J, Lu Z, Wang H, Xu F, Shi L*. MiR-127 Modulates Macrophage Polarization and Promotes Lung Inflammation and Injury by Activating the JNK Pathway. J Immunol.  2015;194(3):1239-51
4. Kang Y, Wang F, Ying H, Lu Z, Zhang  H, Ding W, Wang C, Shi L*. Mitogen-activated protein kinase kinase 3 potentiates Chlamydia HSP60-induced inflammatory response through distinct activation of NF-kappaB. J Immunol. 2013;191(1):386-94.
5. Xu F, Kang Y, Zhang H, Piao Z, Yin H, Diao R, Xia J, Shi L*. Akt1 comprised antibacterial response through regulating macrophage polarization. J Infect Dis. 2013;208(3):528-38
6. Shi L, Leu SW, Xu F, Zhou X, Yin H, Cai L, Zhang L. Local blockade of TSLP receptor alleviated allergic disease by regulating airway dendritic cells. Clin Immunol. 2008,129(2): 202-210.
7. Shi L, Luo K, Xia D, Chen T, Chen G, Jiang Y, Li N, Cao X. DIgR2, dendritic cell–derived immunoglobulin receptor 2, is one representative of a family of IgSF inhibitory receptors and mediates negative regulation of dendritic cell–initiated antigen-specific T-cell responses. Blood. 2006,108(8):2678-2686.